Anyway, I'll babble my head off if you don't shoot me first so let me attempt to get to the point. I want to play my beloved old Sonic games (1, 2, and Spinball) for the Genesis. I downloaded PicoDrive 1.51 and extracted it. I'm using 6.60 PRO-B10 firmware. Other than that, I don't know what you might need to know about my end.
Now I was glancing through the readme.txt file and it looks like there's a lot of settings or plugins or something similar to the PSX and PS2 emulators on the PC which I always just let my son set up. So I'm not accustomed to doing it. So I was hoping for some help in how to set up PicoDrive so I can play my Sonic games. Also, since I see there are 3 different file format combos used with PicoDrive, but obviously CUE/BIN is not really the best, which of the other 2 is best for the Sonic games, if that's a valid question?