From my personal experience (and unfortunately, I've been experiencing crashes a lot), player files seem to be one of the causes of crashes - whether it is large collection, too many decks, some damaged files or whatever - I don't know.
So, I would recommend clean install, without music, with all the sets you want, _without_ your player files and see what happens.
I did this and I'm playing the game from the beginning - It's even more fun
